The Washington Post today carried this article detailing new efforts at duplicating what are widely considered to be the finest violins ever made. By using computer modeling and analysis, a Swedish team thinks they can create a replica Stradivarius violin that is indistinguishable from the original. Since nobody's quite sure how Stradivarius did what he did, it's possible they might succeed.
Then again, considering that music appreciation is sometimes as much about politics and perception as it is about science and craft, there's a very good chance they won't.